Show simple item record

dc.contributor.authorFerré, Daniela Marisol
dc.contributor.authorJotallan, Paola
dc.contributor.authorLentini, Valeria
dc.contributor.authorLudueña, Héctor Ricardo
dc.contributor.authorRomano, Raquel
dc.contributor.authorGorla, Nora Bibiana María
dc.date.accessioned2021-05-19T11:35:15Z
dc.date.available2021-05-19T11:35:15Z
dc.date.issued2020-03-19
dc.identifier.citationDaniela M. Ferré, Paola J. Jotallan, Valeria Lentini, Hector R. Ludueña, Raquel R. Romano, Nora B.M. Gorla, Biomonitoring of the hematological, biochemical and genotoxic effects of the mixture cypermethrin plus chlorpyrifos applications in bovines, Science of The Total Environment,Volume 726,2020,138058, doi.org/10.1016/j.scitotenv.2020.138058.en_US
dc.identifier.issn1879-1026
dc.identifier.otherdoi.org/10.1016/j.scitotenv.2020.138058
dc.identifier.urihttp://repositorio.umaza.edu.ar//handle/00261/2370
dc.description.abstractARTÍCULO PUBLICADO EN REVISTA EXTERNA. External antiparasitic agents applied in bovine production represent a risk to consumers of meat products, espe- cially if the conditions of their use are not strictly respected. The post-mortem control of residues in meat is an activity that must be updated and reinforced by the biomonitoring of live animals and the use of analytical tools to help identifying signs of early warning risks. The objective of the present study was to carry out a pre- slaughter biomonitoring approach in Aberdeen Angus cattle and crosses (n = 12) with the application of a com- mercial formulation of cypermethrin plus chlorpyrifos. This was performed with a single therapeutic dose ap- plied on the backs of the cattle, through hematological, enzymatic, as well as hepatic and renal function analysis in plasma, and then quantifying the genotoxic effect on lymphocytes. Analytical measurements of plasma concentrations of cypermethrin plus chlorpyrifos at 24 h were negative and therefore a low absorption of the compounds was assumed. Measurement of acetyl cholinesterase showed no inhibition after exposure. The concentration of urea increased between 24 h and 168 h post application of the formulation, without show- ing any kidney damage. The rest of the parameters analyzed did not show any variations. This evaluation of he- matological and biochemical effects and of cytokinesis-block micronucleus cytome assay in bovines is proposed as a pre-slaughter control of biomonitoring of the health status of animals, with a focus on food safety for meat consumers.en_US
dc.language.isoengen_US
dc.publisherScience of the Total Environment Editorialen_US
dc.source726;
dc.subjectPre-slaughter controlsen_US
dc.subjectAntiparasiticen_US
dc.subjectCytokinesis-block micronucleus cytome assayen_US
dc.subjectCholinesterasesen_US
dc.subjectCattleen_US
dc.subjectBiomarkersen_US
dc.titleBiomonitoring of the hematological, biochemical and genotoxic effects of the mixture cypermethrin plus chlorpyrifos applications in bovinesen_US
dc.typeArtículo Científicoen_US
umaza.description.filiationFil: Ferré, Daniela. Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Argentina.Universidad Juan Agustín Maza, Laboratorio de Genética, Ambiente y Reproducción, lateral sur 2245, Guaymallén, Mendoza, Argentinaen_US
umaza.description.filiationFil: Jotallan, Paola. Universidad Juan Agustín Maza, Laboratorio de Genética, Ambiente y Reproducción, lateral sur 2245, Guaymallén, Mendoza, Argentinaen_US
umaza.description.filiationFil: Lentini, Valeria. Universidad Juan Agustín Maza. Laboratorio de Genética, Ambiente y Reproducción, lateral sur 2245, Guaymallén, Mendoza, Argentinaen_US
umaza.description.filiationFil: Ludueña, Héctor Ricardo. Universidad Juan Agustín Maza. Laboratorio de Genética, Ambiente y Reproducción, lateral sur 2245, Guaymallén, Mendoza, Argentinaen_US
umaza.description.filiationFil: Romano, Raquel. Universidad Juan Agustín Maza. Laboratorio de Genética, Ambiente y Reproducción, lateral sur 2245, Guaymallén, Mendoza, Argentinaen_US
umaza.description.filiationFil: Gorla, Nora. Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Argentina.Universidad Juan Agustín Maza, Laboratorio de Genética, Ambiente y Reproducción, lateral sur 2245, Guaymallén, Mendoza, Argentinaen_US
umaza.statusSNRDPublicadaen_US


Files in this item

Thumbnail

This item appears in the following Collection(s)

  • Ciencias Veterinarias [36]
    Artículos científicos publicados por equipos de investigación UMaza con resultados de proyectos realizados en las áreas disciplinares: ciencias veterinarias

Show simple item record