Now showing items 1-2 of 2

    • Evaluation of the genotoxic potential of cypermethrin, chlorpyrifos and their subsequent mixture, on cultured bovine lymphocytes 

      Ferré, Daniela Marisol; Ludueña, Héctor Ricardo; Romano, Raquel; Gorla, Nora Bibiana María (Comité editorial Chemosphere Journal, 2019-11-09)
      Cypermethrin (CYP) and chlorpyrifos (CPF) are insecticides/parasiticides used in the production of fruits, vegetables and beef cattle. These substances or their metabolites are frequently reported as residues in food, whose consumption in a diet implies a genotoxic risk. The potential for chronic toxicity of CYP and CPF is unclear, and only a few genotoxicological evaluations based on their mixture have been performed. The aim of this study was to evaluate the genotoxic potential of CYP, CPF and CYP þ CPF in five concentrations, from 5.9 to 175 mg/mL, on bovine lymphocytes. By means of the ...
    • Reference values for acetyl and butyrylcholinesterases in cattle under actual management conditions, hepatic and renal function by application of chlorpyrifos 

      Ferré, Daniela Marisol; Lentini, Valeria Roxana; Romano, Raquel; Ludueña, Héctor Ricardo; Jotallán, Paola Jimena; Gorla, Nora Bibiana María (Comité editorial Journal of Environmental Science and Health, 2018-01-02)
      Chlorpyrifos is an anticholinesterase organophosphate insecticide widely used in Argentina in the production of food derived from animal, fruit and horticultural origin and is reported as a residue within these products. Local reference values for acetyl and butyrylcholinesterase were determined in Aberdeen Angus bovine and cross bred cattle (n D 25), a requirement to be able to evaluate toxicity of commercial organophosphate and carbamate formulations. The activity of cholinesterase enzymes presented an overall mean of 2,183.00 § 485.6 IU L¡1 for erythrocyte acetylcholinesterase and 203.1 § ...