Ovarian carcinoma is one of the most common cause of death by gynecologic cancer. Several epidemiological and in vitro studies have shown controversial data about progesterone effects in ovarian cancer. Progesterone can be converted in its active metabolite, allopregnanolone, its effects in ovarian cancer are still unknown. Previously, we demonstrated that allopregnanolone modifies ovarian morphophysiology, being able to alter critical process of tumor development such as proliferation, apoptosis and angiogenesis. Taking into account these antecedents, we investigated the effect of progesterone ...

Reproduction and fertility are regulated via hormones of the hypothalamic-pituitary-gonadal (HPG) axis. Control of this reproductive axis occurs at all levels, including the brain and pituitary, and allows for the promotion or inhibition of gonadal sex steroid secretion and function. In addition to guiding proper gonadal development and function, gonadal sex steroids also act in negative-and positive-feedback loops to regulate reproductive circuitry in the brain, including kisspeptin neurones, thereby modulating overall HPG axis status. Additional regulation is also provided by sex steroids made ...

Entrevista radial realizada por Morena Esquivel en radio Estación del Sol 100.9 (https://estaciondelsol.elsol.com.ar/) a la directora de proyecto Lizzet Vejling acerca de la investigación realizada en Creatividad Publicitaria en Universidad Juan Agustín Maza junto a equipo de investigación.

Birds have the potential to be considered valuable bioindicators of the quality of ecosystems and the environmental impact of pollutants. The aims of this study were to determine the micronuclei frequency and other nuclear abnormalities in erythrocytes by analyzing a wild bird community from central Monte desert (Argentina) and to clarify if there were any differences among certain species. Frequencies of nuclear abnormalities were determined in 73 wild birds belonging to 17 species and two orders (Passeriformes and Columbiformes). A high proportion of individuals, 90.4 and 80.9 %, had erythrocytes ...

Proyecto de investigación de la capacidad probiótica de Pseudobutyrivibrio xylanivorans para su posible aplicación como herramienta de manipulación de la fermentación rumial en cabras criollas. Preparada para la II Jornadas Internacionales de investigación. Informamos sobre la importancia de bacterias pertenecientes al orden Clostridiales en el ecosistema ruminal de cabras alimentadas con una dieta fibrosa.

Comunicación realizada para el Encuentro de Investigadores de la Red Andina de Unviersidades (RADU), mayo 2011, correspondiente a proyecto de investigación Convocatoria 2009 de la Facultad de Periodismo UMaza.

Cypermethrin (CYP) and chlorpyrifos (CPF) are insecticides/parasiticides used in the production of fruits, vegetables and beef cattle. These substances or their metabolites are frequently reported as residues in food, whose consumption in a diet implies a genotoxic risk. The potential for chronic toxicity of CYP and CPF is unclear, and only a few genotoxicological evaluations based on their mixture have been performed. The aim of this study was to evaluate the genotoxic potential of CYP, CPF and CYP þ CPF in five concentrations, from 5.9 to 175 mg/mL, on bovine lymphocytes. By means of the ...