Browsing Ciencias de la Salud Humana by Subject "Apoptosis"
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Allopregnanolone alters follicular and luteal dynamics during the estrous cycle. (Comité editor Reproductive Biology and Endocrinology, 2018)ARTÍCLO PUBLICADO EN REVISTA EXTERNA. Background: Allopregnanolone is a neurosteroid synthesized in the central nervous system independently of steroidogenic glands; it influences sexual behavior and anxiety. The aim of this work is to evaluate the indirect effect of a single pharmacological dose of allopregnanolone on important processes related to normal ovarian function, such as folliculogenesis, angiogenesis and luteolysis, and to study the corresponding changes in endocrine profile and enzymatic activity over 4 days of the rat estrous cycle. We test the hypothesis that allopregnanolone ...